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Easier way to check if an item from one list of tuples doesn't exist in another list of tuples in python

I have two lists of tuples, say,
list1 = [('item1',),('item2',),('item3',), ('item4',)] # Contains just one item per tuple
list2 = [('item1', 'd',),('item2', 'a',),('item3', 'f',)] # Contains multiple items per tuple
Expected output: 'item4' # Item that doesn't exist in list2
As shown in above example I want to check which item in tuples in list 1 does not exist in first index of tuples in list 2. What is the easiest way to do this without running two for loops?

Assuming your tuple structure is exactly as shown above, this would work:
tuple(set(x[0] for x in list1) - set(x[0] for x in list2))
or per #don't talk just code, better as set comprehensions:
tuple({x[0] for x in list1} - {x[0] for x in list2})
result:
('item4',)

This gives you {'item4'}:
next(zip(*list1)) - dict(list2).keys()
The next(zip(*list1)) gives you the tuple ('item1', 'item2', 'item3', 'item4').
The dict(list2).keys() gives you dict_keys(['item1', 'item2', 'item3']), which happily offers you set operations like that set difference.
Try it online!

This is the only way I can think of doing it, not sure if it helps though. I removed the commas in the items in list1 because I don't see why they are there and it affects the code.
list1 = [('item1'),('item2'),('item3'), ('item4')] # Contains just one item per tuple
list2 = [('item1', 'd',),('item2', 'a',),('item3', 'f',)] # Contains multiple items per tuple
not_in_tuple = []
OutputTuple = [(a) for a, b in list2]
for i in list1:
if i in OutputTuple:
pass
else:
not_in_tuple.append(i)
for i in not_in_tuple:
print(i)

You don't really have a choice but to loop over the two lists. Once efficient way could be to first construct a set of the first elements of list2:
items = {e[0] for e in list2}
list3 = list(filter(lambda x:x[0] not in items, list1))
Output:
>>> list3
[('item4',)]

Try set.difference:
>>> set(next(zip(*list1))).difference(dict(list2))
{'item4'}
>>>
Or even better:
>>> set(list1) ^ {x[:1] for x in list2}
{('item4',)}
>>>

that is a difference operation for sets:
set1 = set(j[0] for j in list1)
set2 = set(j[0] for j in list2)
result = set1.difference(set2)
output:
{'item4'}

for i in list1:
a=i[0]
for j in list2:
b=j[0]
if a==b:
break
else:
print(a)

Replace string in specific index in list of lists python

How can i replace a string in list of lists in python but i want to apply the changes only to the specific index and not affecting the other index, here some example:
mylist = [["test_one", "test_two"], ["test_one", "test_two"]]
i want to change the word "test" to "my" so the result would be only affecting the second index:
mylist = [["test_one", "my_two"], ["test_one", "my_two"]]
I can figure out how to change both of list but i can't figure out what I'm supposed to do if only change one specific index.

Use indexing:
newlist = []
for l in mylist:
l[1] = l[1].replace("test", "my")
newlist.append(l)
print(newlist)
Or oneliner if you always have two elements in the sublist:
newlist = [[i, j.replace("test", "my")] for i, j in mylist]
print(newlist)
Output:
[['test_one', 'my_two'], ['test_one', 'my_two']]

There is a way to do this on one line but it is not coming to me at the moment. Here is how to do it in two lines.
for two_word_list in mylist:
two_word_list[1] = two_word_list.replace("test", "my")

How to make a list of certain items from a different list

For example: list1 = [1t, 1r, 2t, 2r, 3t, 3r...., nt, nr]. How do I make a list list_t that has all t items from list1? I tried using the following for loop:
for i in list1[0:]:
list_t =[i.t]
But this only assigns the first item to list_t.

If your list has the same items repeated at the same time step, then:
list1 = ['1t', '1r', '2t', '2r', '3t', '3r']
# list[start:stop:step]
l2 = list1[0::2]
print(l2)
will solve your problem.
However, if what you mean is that you have a list of strings and you need to extract the strings with t on it, then you can just test if t is in the element, like so:
l2 = list()
for i in list1:
if 't' in i :
l2.append(i)
print(l2)

How to merge n lists together item by item for each list

I want to make one large list for entering into a database with values from 4 different lists. I want it to be like
[[list1[0], list2[0], list3[0], list4[0]], [list1[1], list2[1], list3[1], list4[1]], etc.....]
Another issue is that currently the data is received like this:
[ [ [list1[0], list1[1], [list1[3]]], [[list2[0]]], etc.....]
I've tried looping through each list using indexs and adding them to a new list based on those but it hasn't worked, I'm pretty sure it didn't work because some of the lists are different lengths (they're not meant to be but it's automated data so sometimes there's a mistake).
Anyone know what's the best way to go about this? Thanks.

First list can be constructed using zip function as follows (for 4 lists):
list1 = [1,2,3,4]
list2 = [5,6,7,8]
list3 = [9,10,11,12]
list4 = [13,14,15,16]
res = list(zip(list1,list2,list3,list4))
For arbitrtary number of lists stored in another list u can use *-notation to unpack outer list:
lists = [...]
res = list(zip(*lists))
To construct list of lists for zipping from you data in second issue use flatten concept to it and then zip:
def flatten(l):
res = []
for el in l:
if(isinstance(el, list)):
res += flatten(el)
else:
res.append(el)
return res
auto_data = [...]
res = list(zip(*[flatten(el) for el in auto_data]))
Some clarification at the end:
zip function construct results of the smallest length between all inputs, then you need to extend data in list comprehension in last code string to be one length to not lose some info.

So if I understand correctly, this is your input:
l = [[1.1,1.2,1.3,1.4],[2.1,2.2,2.3,2.4],[3.1,3.2,3.3,3.4],[4.1,4.2,4.3,4.4]]
and you would like to have this output
[[1.1,2.1,3.1,4.1],...]
If so, this could be done by using zip
zip(*l)

Make a for loop which only gives you the counter variable. Use that variable to index the lists. Make a temporary list , fill it up with the values from the other lists. Add that list to the final one. With this you will et the desired structure.
nestedlist = []
for counter in range(0,x):
temporarylist = []
temporarylist.append(firstlist[counter])
temporarylist.append(secondlist[counter])
temporarylist.append(thirdlist[counter])
temporarylist.append(fourthlist[counter])
nestedlist.append(temporarylist)
If all the 4 lists are the same length you can use this code to make it even nicer.
nestedlist = []
for counter in range(0,len(firstlist)): #changed line
temporarylist = []
temporarylist.append(firstlist[counter])
temporarylist.append(secondlist[counter])
temporarylist.append(thirdlist[counter])
temporarylist.append(fourthlist[counter])
nestedlist.append(temporarylist)

This comprehension should work, with a little help from zip:
mylist = [i for i in zip(list1, list2, list3, list4)]
But this assumes all the list are of the same length. If that's not the case (or you're not sure of that), you can "pad" them first, to be of same length.
def padlist(some_list, desired_length, pad_with):
while len(some_list) < desired_length:
some_list.append(pad_with)
return some_list
list_of_lists = [list1, list2, list3, list4]
maxlength = len(max(list_of_lists, key=len))
list_of_lists = [padlist(l, maxlength, 0) for l in list_of_lists]
And now do the above comprehension statement, works well in my testing of it
mylist = [i for i in zip(*list_of_lists)]

If the flatten concept doesn't work, try this out:
import numpy as np
myArray = np.array([[list1[0], list2[0], list3[0], list4[0]], [list1[1], list2[1], list3[1], list4[1]]])
np.hstack(myArray)
Also that one should work:
np.concatenate(myArray, axis=1)
Just for those who will search for the solution of this problem when lists are of the same length:
def flatten(lists):
results = []
for numbers in lists:
for output in numbers:
results.append(output)
return results
print(flatten(n))

Extract substrings from a list into a list in Python

I have a Python list like:
['user#gmail.com', 'someone#hotmail.com'...]
And I want to extract only the strings after # into another list directly, such as:
mylist = ['gmail.com', 'hotmail.com'...]
Is it possible? split() doesn't seem to be working with lists.
This is my try:
for x in range(len(mylist)):
mylist[x].split("#",1)[1]
But it didn't give me a list of the output.

You're close, try these small tweaks:
Lists are iterables, which means its easier to use for-loops than you think:
for x in mylist:
#do something
Now, the thing you want to do is 1) split x at '#' and 2) add the result to another list.
#In order to add to another list you need to make another list
newlist = []
for x in mylist:
split_results = x.split('#')
# Now you have a tuple of the results of your split
# add the second item to the new list
newlist.append(split_results[1])
Once you understand that well, you can get fancy and use list comprehension:
newlist = [x.split('#')[1] for x in mylist]

That's my solution with nested for loops:
myl = ['user#gmail.com', 'someone#hotmail.com'...]
results = []
for element in myl:
for x in element:
if x == '#':
x = element.index('#')
results.append(element[x+1:])