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Timing out while trying to connect to sql in Azure Managed Instance from Azure VM

I am trying to access tables in SQL database in Azure Managed Instance (with IP: xxxx.database.windows.net) from a python script in Azure VM machine but I am getting the Operational Error below. I have tried with 2 different ways below.
Error:
OperationalError: ('08001', '[08001] [Microsoft][SQL Server Native Client 11.0]TCP Provider: A connection attempt failed because the connected party did not properly respond after a period of time, or established connection failed because connected host has failed to respond.\r\n (10060) (SQLDriverConnect); [08001] [Microsoft][SQL Server Native Client 11.0]Login timeout expired (0); [08001] [Microsoft][SQL Server Native Client 11.0]A network-related or instance-specific error has occurred while establishing a connection to SQL Server. Server is not found or not accessible. Check if instance name is correct and if SQL Server is configured to allow remote connections. For more information see SQL Server Books Online. (10060)')
1st way with connectionString:
import pandas as pd
from sqlalchemy import create_engine
engine = create_engine("mssql+pyodbc://<username>:<password>#<server>/<database>?driver=SQL+Server+Native+Client+11.0")
query = "select * from table"
df=pd.read_sql(query,engine)
2nd way with connectionString:
import pyodbc
server = 'xxx.database.windows.net'
database = 'database'
username = 'username'
password = 'password'
driver= '{SQL Server Native Client 11.0}'
with pyodbc.connect('DRIVER='+driver+';SERVER='+server+';PORT=1433;DATABASE='+database+';UID='+username+';PWD='+ password) as conn:
with conn.cursor() as cursor:
cursor.execute("SELECT TOP 3 name, collation_name FROM sys.databases")
row = cursor.fetchone()
while row:
print (str(row[0]) + " " + str(row[1]))
row = cursor.fetchone()
Besides, I have also tried to change the driver to drivers below, still no luck.
{ODBC Driver 11 for SQL Server}
{ODBC Driver 13 for SQL Server}
{ODBC Driver 17 for SQL Server}
{SQL Server Native Client 11.0}
Interesting part is, if I try the connect with the same connection string from on-premise machine which is not Azure VM (ex: my local machine or other servers I can RDP to), I can access the database. But when I try on a Azure VM machine, it is timing out. Do you have any ideas how to fix this problem?
Thank you for inputs.

So in the end we foud out that firewall caused this problem. We need to check firewall rules first.

[SqlAlchemy][mssql][tls1.2] How to enforce TLS 1.2 for SqlAlchemy connecting to MS SQL Server using pyodbc from windows?

Recent hardening standards have made us disable TLS 1.0 and 1.1.
Registry Settings for TLS 1.0 and 1.1:
HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\SecurityProviders\SCHANNEL\Protocols\TLS 1.0\Client
HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\SecurityProviders\SCHANNEL\Protocols\TLS 1.1\Client
Now the following code:
from sqlalchemy import create_engine
db = create_engine(
"mssql+pyodbc://__OUR_SERVER_NAME__/__OUR_DATABSE_NAME__?driver=SQL+Server+Native+Client+11.0&Trusted_Connection=yes&Encrypt=yes&TrustServerCertificate=Yes&ssl=True",
connect_args={
# 'sslmode': 'require', # did not work
# 'tls-version': 'tls1.2', # did not work
# 'ssl': True, # did not work
},
echo=True,
)
with db.begin() as conn:
conn.execute("SELECT TOP 5 * FROM sys.tables")
Will throw this exception on db.begin():
Exception has occurred: OperationalError
(pyodbc.OperationalError) ('08001', '[08001] [Microsoft][SQL Server Native Client 11.0]Encryption not supported on the client. (21) (SQLDriverConnect); [08001] [Microsoft][SQL Server Native Client 11.0]SSL Provider: The client and server cannot communicate, because they do not possess a common algorithm.\r\n (-2146893007); [08001] [Microsoft][SQL Server Native Client 11.0]Client unable to establish connection (21); [08001] [Microsoft][SQL Server Native Client 11.0]Invalid connection string attribute (0); [08001] [Microsoft][SQL Server Native Client 11.0]A network-related or instance-specific error has occurred while establishing a connection to SQL Server. Server is not found or not accessible. Check if instance name is correct and if SQL Server is configured to allow remote connections. For more information see SQL Server Books Online. (-2146893007)')
TLS 1.2 is enabled and works fine with Azure Data Studio on the same client server.
Even python shows openssl version is resonable:
import ssl
print(f'SSL Version = {ssl.OPENSSL_VERSION}')
which outputs:
SSL Version = OpenSSL 1.1.1d 10 Sep 2019
Python version:
python --version
Python 3.7.6
I have tried looking at SSLContext but can't seem to find how to make it work with SqlAlchemy.
Any help would be greatly appreciated!!!
Possible duplicate question (with less info): Connecting to SQL Server using pyodc with TLS 1.2

Further investigation showed an issue with the ODBC driver.
The app was on Windows Server 2012 with ODBC version:
SQL Server Native Client 11.0
Version: 2011.110.3000.00
Date: 10/20/2012
Updating the driver to ODBC Driver 17 for SQL Server with new connection string worked:
from sqlalchemy import create_engine
db = create_engine(
"mssql+pyodbc://__OUR_SERVER_NAME__/__OUR_DATABSE_NAME__?driver=ODBC+Driver+17+for+SQL+Server&Trusted_Connection=yes&Encrypt=yes&TrustServerCertificate=Yes&ssl=True",
connect_args={
# 'sslmode': 'require', # did not work
# 'tls-version': 'tls1.2', # did not work
# 'ssl': True, # did not work
},
echo=True,
)

python connection with SQL server

I used the pyodbc and pypyodbc python package to connect to SQL server.
Drivers used anyone of these ['SQL Server', 'SQL Server Native Client 10.0', 'ODBC Driver 11 for SQL Server', 'ODBC Driver 13 for SQL Server'].
connection string :
connection = pyodbc.connect('DRIVER={SQL Server};'
'Server=aaa.database.windows.net;'
'DATABASE=DB_NAME;'
'UID=User_name;'
'PWD=password')
now I am getting error message like
DatabaseError: (u'28000', u"[28000] [Microsoft][ODBC SQL Server Driver][SQL Server]Login failed for user
But I can connect to the server through the SQL server management studio.
its on SQL Server Authentication, Not Windows Authentication.
Is this about python package and driver issue or DB issue??? how to solve?

You can add Trusted_Connection=NO; in your connection string after the password

I see you have no port defined in your script.
The general way to connect to a server using pyodbc ${DBName} ${DBUser} ${DBPass} ${DBHost} ${DBPort}, where DBName is your database name, DBUser is the username used to connect to it, DBPass is the password, DBHost is the URL of your database, and DBPort is the port you use to connect to your DB.
I use MS SQL so my port is 1433, yours might be different.
I've had this issue just today, and that fixed it.

The problem is not driver issue, you can see the error message is DatabaseError: Login failed for user, it means this problem occurs if the user tries to log in with credentials that cannot be validated. I suspect you are login with your windows Authentication, if so, use Trusted_Connection=yes instead:
connection = pyodbc.connect('DRIVER={SQL Server};Server=aaa.database.windows.net;DATABASE=DB_NAME;Trusted_Connection=yes')
For more details, please refer to my old answer about the difference of SQL Server Authentication modes.

I think problem because of driver definition in your connection string. You may try with below.
connection = pyodbc.connect('DRIVER={SQL Server Native Client 10.0}; Server=aaa.database.windows.net; DATABASE=DB_NAME; UID=User_name; PWD=password')

I applied your connection string and updated it with my server connections details and it worked fine.
Are you sure your are passing correct user name and password ?
Login failed implies connection was established successfully, but authentication didn't pass.

Error 28000: Login failed for user DOMAIN\\user with pyodbc

I am trying to use Python to connect to a SQL database by using Window authentication. I looked at some of the posts here (e.g., here), but the suggested methods didn't seem to work.
For example, I used the following code:
cnxn = pyodbc.connect(driver='{SQL Server Native Client 11.0}',
server='SERVERNAME',
database='DATABASENAME',
trusted_connection='yes')
But I got the following error:
Error: ('28000', "[28000] [Microsoft][SQL Server Native Client 11.0][SQL Server]
Login failed for user 'DOMAIN\\username'. (18456) (SQLDriverConnect); [28000] [Microsoft]
[SQL Server Native Client 11.0][SQL Server]Login failed for user 'DOMAIN\\username'.
(18456)")
(Note that I replaced the actual domain name and user name with DOMAIN and username respectively, in the error message above.)
I also tried using my UID and PWD, which led to the same error.
Lastly, I tried to change the service account by following the suggestion from the link above, but on my computer, there was no Log On tab when I went to the Properties of services.msc.
I wonder what I did wrong and how I can fix the problem.

Connecting from a Windows machine:
With Microsoft's ODBC drivers for SQL Server, Trusted_connection=yes tells the driver to use "Windows Authentication" and your script will attempt to log in to the SQL Server using the Windows credentials of the user running the script. UID and PWD cannot be used to supply alternative Windows credentials in the connection string, so if you need to connect as some other Windows user you will need to use Windows' RUNAS command to run the Python script as that other user..
If you want to use "SQL Server Authentication" with a specific SQL Server login specified by UID and PWD then use Trusted_connection=no.
Connecting from a non-Windows machine:
If you need to connect from a non-Windows machine and the SQL Server is configured to only use "Windows authentication" then Microsoft's ODBC drivers for SQL Server will require you to use Kerberos. Alternatively, you can use FreeTDS ODBC, specifying UID, PWD, and DOMAIN in the connection string, provided that the SQL Server instance is configured to support the older NTLM authentication protocol.

I tried everything and this is what eventually worked for me:
import pyodbc
driver= '{SQL Server Native Client 11.0}'
cnxn = pyodbc.connect(
Trusted_Connection='Yes',
Driver='{ODBC Driver 11 for SQL Server}',
Server='MyServer,1433',
Database='MyDB'
)

Try this cxn string:
cnxn = pyodbc.connect('DRIVER={SQL Server};SERVER=localhost;PORT=1433;DATABASE=testdb;UID=me;PWD=pass')
http://mkleehammer.github.io/pyodbc/

I had similar issue while connecting to the default database (MSSQLSERVER). If you are connecting to the default database, please remove the
database='DATABASENAME',
line from the connection parameters section and retry.
Cheers,
Deepak

The first option works if your credentials have been stored using the command prompt. The other option is giving the credentials (UId, Psw) in the connection.
The following worked for me:
conn = pyodbc.connect('DRIVER={SQL Server};SERVER=yourServer;DATABASE=yourDatabase;UID=yourUsername;PWD=yourPassword')

import pyodbc #For python3 MSSQL
cnxn = pyodbc.connect("Driver={SQL Server};" #For Connection
"Server=192.168.0.***;"
"PORT=1433;"
"Database=***********;"
"UID=****;"
"PWD=********;")
cursor = cnxn.cursor() #Cursor Establishment
cursor.execute('select site_id from tableName') #Execute Query
rs = cursor.fetchall()
print(rs)

A slightly different use case than the OP, but for those interested it is possible to connect to a MS SQL Server database using Windows Authentication for a different user account than the one logged in.
This can be achieved using the python jaydebeapi module with the JDBC JTDS driver. See my answer here for details.

Note that you may need to change the authentication mechanism. For example, my database is using ADP. So my connection looks like this
pyodbc.connect(
Trusted_Connection='No',
Authentication='ActiveDirectoryPassword',
UID=username,
PWD=password,
Driver=driver,
Server=server,
Database=database)
Read more here

Trusted_connection=no did not helped me. When i removed entire line and added UID, PWD parameter it worked. My takeaway from this is remove

Windows Authentication with MySQLdb in Python

Is there a way to connect to MySQL database with Windows Authentication in Python? It is enabled on MySQL server, I login into it with Microsoft MySQL Server Management Studio no problem. However, usual setup:
import MySQLdb
db = MySQLdb.connect(host="sampleserver\\demo",
db="sample")
doesnt seem to work. In fact, host is not even recognized. Our DBA didnt give me a endpoint aside from that host. It works for the Management Studio.
Edit 1
As per suggestion in the answer, tried connecting with the connection string method with pyodbc library.
import pyodbc
cnxn = pyodbc.connect("DRIVER={SQL Server};"
"SERVER=server_name\\demo;"
"DATABASE=sample;"
"UID=auth_windows")
Double backslash, I'm escaping the backsalsh in the server name
Getting fairly long error message:
Error: ('28000', "[28000] [Microsoft][ODBC SQL Server Driver][SQL Server]Login failed for user 'auth_windows'. (18456) (SQLDriverConnect);
[28000] [Microsoft][ODBC SQL Server Driver][SQL Server]Login failed for user 'auth_windows'. (18456)")
When I tried to add IntegratedSecurity=yes, I also get:
[01S00] [Microsoft][ODBC SQL Server Driver]Invalid connection string attribute (0)

This is the connection string you need to use:
Server=myServerAddress;Database=myDataBase;IntegratedSecurity=yes;Uid=auth_windows;
This option is available from Connector/NET version 6.4.4, but please note that is requires the Windows Native Authentication Plugin must to be installed.

Based on Jaco's answer but pyodbc library requires slightly different string, or it will produce unrecognized attribute error:
Server=myServerAddress;Database=myDataBase;Trusted_Connection=yes;Uid=auth_window;