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get replys to a specific tweet with twitter api v2

anyone knows how to get a the relys for a specific tweet by it's ID maybe? i been trying but can't find any on the tweepy docs not discord's, can't seem to find anything about how to do it with twitter api v2, also is there a way to requests latest tweets from multiple users in bulk?
import tweepy
twitter_client = tweepy.Client(bearer_token=bearer)
all_tweets = twitter_client.get_users_tweets(id=(1334299956241461248,1346973288040263680,154449778,1516418305455763466))
print(all_tweets)
this is how i try it, but it's returning me an error
The `id` query parameter value [(1334299956241461248, 1346973288040263680, 154449778, 1516418305455763466)] is not valid
any help appreiciated, and thank you

and i found the answer at the end
def check_replys(tweet_ID):
query = f"conversation_id:{tweet_ID} is:reply"
replys= twitter_client.search_recent_tweets(query= query )
return replys
you can find more info about making a query at https://developer.twitter.com/en/docs/twitter-api/tweets/search/integrate/build-a-query

You're asking two questions:
How to get replies by Tweet ID
How to lookup the latest Tweets for several users
For 1 - you can search for Tweets by conversation ID. The conversation ID is the ID of the original Tweet that led to the replies. The only wrinkle here is that by default (v2 Essential access) you can only search for Tweets within the past 7 days, so if the Tweet you want replies for is older than that, you'll need Academic access for full archive search.
For 2 - you cannot pass multiple values to the id parameter all at once. If you look at the Tweepy documentation and at the Twitter API docs, you'll see that id gets substituted into the URL path for the call, so you have to call the API multiple times, one for each user ID. That should be possible using a loop.

Twitter API: How to Get the Topic of Tweets?

I am trying to pull the Category/Topic of Tweets for a school project.
I am not seeing it as one of the keys in public_tweets (below), was wondering if it was located within a variable somewhere else? Thanks!
Example of a Twitter Topic/Category (would like to pull the “Lebron James” label):

Topics are known as “context annotations” in the Twitter API, and are only available in v2. The Tweet data you have here is from v1.1. You’ll need to update the way you are accessing the API and add parameters to get Tweet expansions and fields for context annotations.

How to get tweets in real time from a user's timeline using Tweepy

I'm trying to pull tweets from a user's timeline in real-time. I then want to do some analysis on those tweets. Having read the docs it looks like I will need to use tweepy.Stream for this use case. I've done the following:
stream.filter(follow='25073877')
But Twitter's filter API states the following:
Tweets created by the user.
Tweets which are retweeted by the user.
Replies to any Tweet created by the user.
Retweets of any Tweet created by the user.
Manual replies, created without pressing a reply
button (e.g. “#twitterapi I agree”).
It seems that this will return a huge volume of tweets that aren't relevant to my use case. Do I have to use this approach and then filter by screen name to get only tweets by the real user? This doesn't seem right at all.
The alternative seems to be the api.user_timeline class but that isn't a streaming API. Do I therefore use this API and hit it every second? I can't seem to find suitable examples of how best to accomplish my use case.

Yes, you'll need to filter either by screen_name or maybe you can check if it's a retweet or not.
I wouldn't recommend the second approach since you'll be getting an even bigger amount of tweets since you'll have to filter out the tweets you already received in previous requests plus you may hit the API querying limits if you don't time ti properly.
That's the signature of the filter function:
def filter(self, follow=None, track=None, is_async=False, locations=None,
stall_warnings=False, languages=None, encoding='utf8', filter_level=None)
Which maps to this Twitter API request.
And here the explanation of the parameters.

Twitter API - Retrieve all replies to a certain tweet

I am trying to use Twitter API with the Python wrapper Twython and I want to retrieve all replies (the comments below a tweet) to a certain tweet find using some patterns.
At the moment to achieve this, I perform the search of a string, I retrieve the screen_name field of user field in the response, related to the original tweets and then I use again the API in order to search the latest tweets directed to the user, using in the query the substring to:screen_name.
Is there a better solution? The only questions related to this topic that I found were written in '14 and I hope that, in the mean time, there were some improvements.

Get all tweets from a user using python-twitter

I'm trying to retrieve all the tweets from a user in python with this lib.
The method provided in python-twitter to do this is defined as :
def GetUserTimeline(self,
user_id=None,
screen_name=None,
since_id=None,
max_id=None,
count=None,
include_rts=None,
trim_user=None,
exclude_replies=None):
Though if the count is limited to 200.
Documentation:
count:
Specifies the number of statuses to retrieve. May not be
greater than 200. [Optional]
My question now is: Is it possible to retrieve all the tweets from a user with this lib ? And is there an alternative solution ?

Short answer: no.
Twitter API explicitly says that you cannot retrieve more then 200 tweets from a user per request so this is not a limitation of this particular library you're using but a limitation imposed by Twitter. But keep in mind that this is per request, if you will send multiple requests you can get up to 3200 tweets in total. But this still means that you can't get all tweets, only 3200.
Here is official Twitter API statuses/user_timeline endpoint documentation.